Santos R, Aldred N, Gorb S and Flammang P. 2013. Biological and Biomimetic Adhesives. Challenges and Opportunities. RSC Publishing, Cambridge, 186pp (ISBN 978-1-84973-669-5).



Book chapters

Flammang P, Demeuldre M, Hennebert E, Santos R. 2016. Adhesive secretions in echinoderms: A review. In: Biological Adhesives, 2nd edition (ed. Andrew M. Smith), Berlin, Springer-Verlag (ISBN 978-3-319-46082-6).



Del Campo A, Schwotzer W, Gorb SN, Aldred N, Santos R, Flammang P. 2013. Biological and Biomimetic Adhesives – Challenges and Opportunities (Santos R, Aldred N, Gorb S and P Flammang Eds.), Royal Society of Chemistry (ISBN 978-1-84973-669-5)



Soares R, Pires E, Almeida A, Santos R, Gomes R, Koci K, Franco C, Coelho AV. 2012. Tandem Mass Spectrometry of peptides, In: Tandem Mass Spectrometry – Applications e Principles, (ed. Jeevan K. Prasain), InTech, pp. 35-56 (ISBN 978-953-51-0141-3).



Santos R, Hennebert E, Varela Coelho A, Flammang P. 2009. Echinoderm tube foot surface e its role in temporary underwater adhesion. In: Functional Surfaces in Biology (ed. S. Gorb), Berlin, Springer-Verlag, pp. 9-41 (ISBN 978-1-4020-6695-5)



Flammang P, Santos R, Haesaerts D. 2005. Echinoderm adhesive secretions: From experimental characterization to biotechnological applications In: Progress in Molecular e Subcellular Biology, Marine Molecular Biotechnology, Echinodermata (ed. V. Matranga), Berlin, Springer Verlag, pp.199-217 (ISBN 978-3-540-27683-8).



Reis CS, Dornelas M, Lemos R, Santos R. 2002. Fisheries. In: Climate Change in Portugal. Scenarios, impacts e adaptation measures. SIAM Project. (eds. F. P. Santos, K. Forbes e R. Moita), Lisbon, Gradiva, pp. 415-454 (Depósito legal: 181 782/2002).



International peer-reviewed journals


Gaspar L, Flammang P, José  R, Luis R, Ramalhosa P, Monteiro J, Nogueira N, Canning-Clode J and Santos R (2021) Interspecific analysis of sea urchin adhesive composition emphasizes variability of glycans conjugated with putative adhesive proteins. Front. Mar. Sci.


Davey PA, Power AM, Santos R, Bertemes P, Ladurner P, Palmowski P, Clarke J, Flammang P, Lengerer B, Hennebert E, Rothbächer U, Pjeta R, Wunderer J, Zurovec M, Aldred N. Omics-based molecular analyses of adhesion by aquatic invertebrates. Biological Reviews.



Simão M, Moço M, Marques L, Santos R. Characterization of the glycans involved in sea urchin Paracentrotus lividus reversible adhesion. Marine Biology.


Pjeta R, Lindner H, Kremser L, Salvenmoser W, Sobral D, Ladurner P, Santos R. Integrative Transcriptome and Proteome Analysis of the Tube Foot and Adhesive Secretions of the Sea Urchin Paracentrotus lividus. International Journal of Molecular Sciences.



Viana AS, Santos R. Nanoscale characterization of the temporary adhesive of the sea urchin Paracentrotus lividus. Beilstein Journal of Nanotechnology.



Lebesgue N, da Costa G, Ribeiro RM, Ribeiro-Silva C, Martins GG, Matranga V, Scholten A, Cordeiro C,  Heck AJR, Santos R. Deciphering the molecular mechanisms underlying sea urchin reversible adhesion: A quantitative proteomics approach. Journal of Proteomics 138:61-71.

Lebesgue N, da Costa G, Ribeiro RM, Ribeiro-Silva C, Martins GG, Matranga V, Scholten A, Cordeiro C, Heck AJR, Santos R. Proteomic dataset of the sea urchin Paracentrotuslividus adhesive organs and secreted adhesive. Data in Brief 7: 1497–1505.

Toubarro D, Gouveia A, Ribeiro RM, Simões N, da Costa G, Cordeiro C, Santos R. Cloning, characterization and expression levels of the Nectin gene from the tube feet of the sea urchin Paracentrotus lividusMarine Biotechnology 18(3):372–383.



Flammang P, Santos R. Biological adhesives: from biology to biomimetics. Interface Focus 5: 20140086.

Hennebert E, Maldonado B, Ladurner P, Flammang P, Santos R. Experimental strategies for the identification and characterization of adhesive proteins in animals: a review. Interface Focus 5: 20140064.



Franco CF, Santos R, Coelho AV. Proteolytic events are relevant cellular responses during nervous system regeneration of the starfish Marthasterias glacialis. Jornal of Proteomics. 99:1-25.



Santos R, Barreto A, Franco CF, Coelho AV. Mapping sea urchins tube feet proteome – a unique hydraulic mechano-sensory adhesive organ. Journal of Proteomics. 79:100-13.


Santos R. A multidisciplinary analysis of sea-urchin temporary adhesion: morphology, biomechanics and proteomics―A review. Cahiers de biologie marine 54 (4), 479-489


Franco C, Soares R, Pires E, Koci K, Almeida AM, Santos R, Coelho AV. Understanding regeneration through proteomics. Proteomics. 13(3-4):686-709.



Flammang P, Santos R. Is the adhesive material secreted by sea urchin tube feet species-specific? Journal of Morphology 273:40-48


Hennebert E, Santos R, Flammang P. Echinoderms don’t suck: evidence against the involvement of suction in tube foot attachment. Zoosymphosia 7

Ribeiro  AR, Barbaglio A, Oliveira MJ, Santos R, Coelho AV, Ribeiro CC, Wilkie IC, Carnevali MDC, Barbosa MA. Correlations between the biochemistry and mechanical states of a sea-Urchin ligament: A mutable collagenous structure. Biointerphases 7:15-15.

Almeida AM, Parreira JR, Santos R, Duque AS, Francisco R, Tome DF, Ricardo, CP,  Coelho AV, Fevereiro P. A proteomics study of theinduction of somatic embryogenesis in Medicago truncatula using 2DE and MALDI-TOF/TOF. Physiologia Plantarum 146:236-249.

Franco CF, Soares, Pires E, Santos R, Coelho AV. Radial nerve cord protein phosphorylation dynamics during starfish arm tip wound healing events. Electrophoresis 33:3764-3778.

Franco CF, Santos R, Coelho AV. Exploring the proteome of an echinoderm nervous system: 2-DE of the sea star radial nerve cord and the synaptosomal membranes subproteome. Proteomics 11:1359-64.



Franco CF, Santos R, Coelho AV. Proteome characterization of sea star coelomocytes – the innate immune effector cells of echinoderms. Proteomics.   11:3587-92.

Lamy E, da Costa G, Santos R, Silva FCE, Potes J, Pereira A, Coelho AV, Baptista ES. Effect of condensed tannin ingestion in sheep and goat parotid saliva proteome. Journal of Animal Physiology and Animal Nutrition 95:304-312.



Toubarro D, Lucena-Robles M, Nascimento G, Santos R, Montiel R, Verissimo P, Pires E, Faro C, Coelho AV, Simões N. Serine Protease-mediated Host Invasion bythe Parasitic Nematode Steinernema carpocapsae. Journal of Biological Chemistry 285: 30666-30675.



Lamy E, da Costa G, Santos R, Silva FCE, Potes J, Pereira A, Coelho AV, Baptista ES. Sheep and goat saliva proteome analysis: A useful tool for ingestive behavior research? Physiology & Behavior 98:393-401.


Santos R, da Costa G, Franco C, Gomes-Alves P, Flammang P, Coelho AV. First insights into the biochemistry of tube footadhesive from the sea urchin Paracentrotus lividus (Echinoidea, Echinodermata). Marine biotechnology 11: 686-98.


Santos R, Flammang P. Estimation of the attachment strength of the shingle sea urchin, Colobocentrotus atratus, and comparison with three sympatric echinoids. Marine Biology 154:37-49.



Santos R, Flammang P. Intra- and interspecific variation of the attachmentstrength in sea urchins. Marine Ecology Progress Series 332:129-142.



Santos R, Flammang P. Morphology and tenacity of tube foot disc of three common European sea urchin species: a comparative study. Biofouling, 22:187-200.



Santos R, Gorb S, Jamar V, Flammang P. Adhesion of echinoderm tube feet to rough surfaces. Journal of Experimental Biology 208:2555-2567.


Santos R, Haesaerts D, Jangoux M, Flammang P. The tube feet of sea urchins and sea stars enclose functionally different mutable collagenous tissues. Journal of Experimental Biology 208:2277-2288.


Santos R, Flammang P. Morphometry and mechanical design of tube footstem in sea urchins: A comparative study. Journal of Experimental Marine Biology and Ecology 315:211-223.



Santos R, Haesaerts D, Jangoux M, Flammang P. Comparative histological and immunohistologicalstudy of sea star tube feet (Echinodermata, Asteroidea). Journal of Morphology. 263:259-269.